Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8483226 | 0.84 | MEN1 (0.61) | MEN1KMT2AALDH1A1PKMCA12 | |
| SCHEMBL8487980 | 0.81 | KMT2A (0.66) | MEN1KMT2AALDH1A1PKMCA12 | |
| SCHEMBL7983776 | 0.80 | CYP19A1 (0.78) | ALDH1A1CACNA1HCACNA1BHTTLMNA | |
| SCHEMBL8487955 | 0.79 | MEN1 (0.55) | MEN1KMT2AALDH1A1PKMCA12 | |
| SCHEMBL8525321 | 0.79 | MEN1 (0.55) | MEN1KMT2AALDH1A1PKMCA12 | |
| SCHEMBL7972331 | 0.79 | CYP19A1 (0.76) | ALDH1A1CACNA1HCACNA1BHTTLMNA | |
| SCHEMBL7983880 | 0.79 | CYP19A1 (0.76) | ALDH1A1CACNA1HCACNA1BHTTLMNA | |
| SCHEMBL7094852 | 0.78 | ALDH1A1 (0.79) | MEN1KMT2AALDH1A1PKMCA12 | |
| SCHEMBL8525293 | 0.78 | CYP2D6 (0.51) | MEN1KMT2ACACNA1HCACNA1BCA2 | |
| SCHEMBL22558321 | 0.78 | CYP19A1 (0.59) | MEN1KMT2AALDH1A1PKMCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792873-A1 | N-(Phenoxyalkyl) carboxamides and their use as antiarrhythmic agents | American Cyanamid Company (US) | 1997-09-03 | — | — | EP | claimed |
| US-5877196-A | N- 4-(imidazolyl or pyrazolyl)phenyl(oxy, sulfinyl, sulfenyl or sulfonyl)alkyl!carboxamides, sulfonamides or phosphoramides having antiarrhythmic properties | AMERICAN CYANAMID COMPANY (US) | 1999-03-02 | — | — | US | disclosed |
| EP-0806424-A1 | Process for producing cephalosporin antibiotics | RANBAXY LABORATORIES, LTD. (IN) | 1997-11-12 | — | — | EP | disclosed |
| EP-0792873-A1 | N-(Phenoxyalkyl) carboxamides and their use as antiarrhythmic agents | American Cyanamid Company (US) | 1997-09-03 | — | — | EP | disclosed |