Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 20/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6724098 | 0.85 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL6726365 | 0.82 | PTGS2 (0.79) | PTGS2 | |
| SCHEMBL6724238 | 0.82 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL8487848 | 0.81 | PTGS2 (0.69) | PTGS2 | |
| SCHEMBL4214071 | 0.81 | PTGS2 (0.69) | PTGS2 | |
| SCHEMBL215130 | 0.80 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL6913549 | 0.79 | PTGS2 (0.65) | PTGS2 | |
| SCHEMBL16561682 | 0.79 | PTGS2 (0.62) | PTGS2 | |
| SCHEMBL16917006 | 0.79 | PTGS2 (0.70) | PTGS2 | |
| SCHEMBL14163957 | 0.79 | PTGS2 (0.70) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932586-A | ANTIINFLAMMATORY AGENTS; ANTIPYRETICS | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-08-03 | — | — | US | claimed |
| US-5932586-A | ANTIINFLAMMATORY AGENTS; ANTIPYRETICS | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-08-03 | — | — | US | disclosed |