Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.64 |
| ▸ | FFAR1 | O14842 | 13/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 10/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10608032 | 0.95 | LTA4H (0.57) | LTA4HEPHX2FFAR1FFAR4FOLH1 | |
| SCHEMBL13870541 | 0.92 | FFAR1 (0.56) | LTA4HEPHX2FFAR1FFAR4FOLH1 | |
| SCHEMBL11621301 | 0.88 | FFAR1 (0.60) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL4002167 | 0.86 | FFAR1 (0.55) | LTA4HEPHX2FFAR1FFAR4FOLH1 | |
| SCHEMBL3993570 | 0.86 | FFAR1 (0.58) | LTA4HEPHX2FFAR1FFAR4HTT | |
| SCHEMBL3997793 | 0.85 | LTA4H (0.56) | LTA4HEPHX2FFAR1FFAR4AKR1B1 | |
| SCHEMBL11614598 | 0.85 | FFAR1 (0.59) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL11617007 | 0.85 | FFAR1 (0.59) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL10689361 | 0.84 | FFAR1 (0.71) | FFAR1FFAR4AKR1B1 | |
| Hydrochloric Acid SCHEMBL6157166 | 0.83 | MAOB (0.63) | FFAR1FFAR4FOLH1AKR1B1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5917057-A | USEFUL AS ANALGESICS AND TOPICAL ANTIINFLAMMATORY AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1999-06-29 | — | — | US | disclosed |
| US-5840749-A | ANALGESICS, INHIBITORS OF CYCLOOXYGENASE AND/OR LIPOXYGENASE, TREATMENT OF DERMATOSES | HOECHST MARION ROUSSEL, INC. (US) | 1998-11-24 | — | — | US | disclosed |
| EP-0419844-B1 | N-hydroxy-dibenz[b,e]oxepin-alkylamines and -alkanoic acid amides, related heterocyclic analogues, a process for their preparation and their use in the manufacture of medicaments | HOECHST ROUSSEL PHARMA (US) | 1995-04-05 | — | — | EP | disclosed |
| EP-0419844-A1 | N-hydroxy-dibenz[b,e]oxepin-alkylamines and -alkanoic acid amides, related heterocyclic analogues, a process for their preparation and their use in the manufacture of medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-04-03 | — | — | EP | disclosed |