Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8502791 | 0.69 | F2 (0.65) | F2 | |
| SCHEMBL22602813 | 0.68 | HSD11B1 (0.70) | HSD11B1TP53ALDH1A1MEN1KMT2A | |
| SCHEMBL885302 | 0.66 | HPGD (0.53) | HSD11B1TP53ALDH1A1MEN1KMT2A | |
| SCHEMBL931218 | 0.66 | HPGD (0.53) | HSD11B1TP53ALDH1A1MEN1KMT2A | |
| SCHEMBL6792635 | 0.65 | ACE (0.75) | ACEMAPTLMNA | |
| Hydrochloric Acid SCHEMBL5392447 | 0.65 | HPGD (0.52) | HSD11B1TP53ALDH1A1MEN1KMT2A | |
| SCHEMBL930717 | 0.64 | HPGD (0.50) | HSD11B1TP53ALDH1A1MEN1KMT2A | |
| SCHEMBL5517503 | 0.64 | HSD11B1 (0.70) | HSD11B1TP53ALDH1A1MEN1KMT2A | |
| SCHEMBL3952911 | 0.64 | HSD11B1 (0.70) | HSD11B1TP53ALDH1A1MEN1KMT2A | |
| SCHEMBL5741139 | 0.64 | ACE (0.59) | ACEHSD11B1TP53MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054017-B1 | Salts of thrombin inhibitors | ABBOTT GMBH & CO KG (DE) | 2004-10-13 | — | — | EP | disclosed |