Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 17/20 | 0.60 |
| ▸ | CASP7 | P55210 | 16/20 | 0.60 |
| ▸ | CASP9 | P55211 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15013035 | 0.88 | CASP3 (0.64) | CASP3CASP7CASP9KCNH2HRH3 | |
| SCHEMBL15013036 | 0.88 | CASP3 (0.64) | CASP3CASP7CASP9KCNH2HRH3 | |
| SCHEMBL12169307 | 0.88 | CASP3 (0.64) | CASP3CASP7CASP9KCNH2HRH3 | |
| SCHEMBL14132624 | 0.87 | CASP3 (0.57) | CASP3CASP7CASP9KCNH2HRH3 | |
| SCHEMBL15800500 | 0.86 | CASP3 (0.64) | CASP3CASP7CASP9KCNH2HRH3 | |
| SCHEMBL15256571 | 0.86 | CASP3 (0.64) | CASP3CASP7CASP9KCNH2HRH3 | |
| SCHEMBL791701 | 0.86 | CASP3 (0.59) | CASP3CASP7CASP9KCNH2HRH3 | |
| SCHEMBL12188937 | 0.85 | KCNH2 (0.64) | CASP3CASP7CASP9KCNH2HRH3 | |
| SCHEMBL12188954 | 0.85 | KCNH2 (0.64) | CASP3CASP7CASP9KCNH2HRH3 | |
| SCHEMBL12169355 | 0.84 | CASP3 (0.57) | CASP3CASP7CASP9KCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999032466-A1 | SUBSTITUTED BENZENESULFONAMIDE DERIVATIVES AND THEIR PHARMACEUTICAL USE | NOVARTIS AG (CH) | 1999-07-01 | — | — | WO | disclosed |