Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | FNTA | P49354 | 2/20 | 0.42 |
| ▸ | FNTB | P49356 | 2/20 | 0.42 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | CCR3 | P51677 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PNKP | Q96T60 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8486503 | 1.00 | POLB (0.42) | POLBFNTAFNTBPGGT1BMEN1 | |
| SCHEMBL8500425 | 0.93 | POLB (0.41) | POLBFNTAFNTBPGGT1BMEN1 | |
| SCHEMBL8500431 | 0.93 | POLB (0.41) | POLBFNTAFNTBPGGT1BMEN1 | |
| SCHEMBL8498504 | 0.88 | POLB (0.41) | POLBFNTAFNTBPGGT1BMEN1 | |
| SCHEMBL8496877 | 0.88 | POLB (0.41) | POLBFNTAFNTBPGGT1BMEN1 | |
| SCHEMBL8502986 | 0.84 | MAPT (0.40) | POLBFNTAFNTBPGGT1BMEN1 | |
| SCHEMBL8343756 | 0.84 | POLB (0.45) | POLBFNTAFNTBPGGT1BMEN1 | |
| SCHEMBL8481493 | 0.83 | POLB (0.44) | POLBFNTAFNTBPGGT1BMEN1 | |
| SCHEMBL8495248 | 0.82 | FNTA (0.40) | POLBFNTAFNTBPGGT1BMEN1 | |
| SCHEMBL8495251 | 0.82 | FNTA (0.40) | POLBFNTAFNTBPGGT1BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999012912-A1 | THIOUREA DERIVATIVES OR NON-TOXIC SALTS THEREOF FOR INHIBITNG RAS-TRANSFORMED CELL GROWTH | YUHAN CORPORATION (KR) | 1999-03-18 | — | — | WO | disclosed |