Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | FNTA | P49354 | 3/20 | 0.39 |
| ▸ | FNTB | P49356 | 3/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8486501 | 0.84 | POLB (0.42) | MAPTPOLBFNTAFNTBPGGT1B | |
| SCHEMBL8486503 | 0.84 | POLB (0.42) | MAPTPOLBFNTAFNTBPGGT1B | |
| SCHEMBL8496877 | 0.83 | POLB (0.41) | MAPTPOLBFNTAFNTBPGGT1B | |
| SCHEMBL8498504 | 0.83 | POLB (0.41) | MAPTPOLBFNTAFNTBPGGT1B | |
| SCHEMBL8500425 | 0.83 | POLB (0.41) | MAPTPOLBFNTAFNTBPGGT1B | |
| SCHEMBL8500431 | 0.83 | POLB (0.41) | MAPTPOLBFNTAFNTBPGGT1B | |
| SCHEMBL8502143 | 0.81 | POLB (0.39) | MAPTTDP1POLBFNTAFNTB | |
| SCHEMBL8343756 | 0.81 | POLB (0.45) | MAPTPOLBFNTAFNTBPGGT1B | |
| SCHEMBL8481493 | 0.79 | POLB (0.44) | MAPTPOLBFNTAFNTBPGGT1B | |
| SCHEMBL8495248 | 0.72 | FNTA (0.40) | MAPTPOLBFNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999012912-A1 | THIOUREA DERIVATIVES OR NON-TOXIC SALTS THEREOF FOR INHIBITNG RAS-TRANSFORMED CELL GROWTH | YUHAN CORPORATION (KR) | 1999-03-18 | — | — | WO | disclosed |