Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8486547 | 0.80 | MEN1 (0.42) | MEN1KMT2AAOX1CETPNPSR1 | |
| SCHEMBL8487370 | 0.79 | CETP (0.49) | MEN1KMT2ACETPLPAR1LPAR3 | |
| SCHEMBL27537966 | 0.79 | MEN1 (0.41) | MEN1KMT2AAOX1CETPLPAR1 | |
| SCHEMBL8412588 | 0.76 | MEN1 (0.49) | MEN1KMT2AAOX1CETP | |
| SCHEMBL8487302 | 0.76 | MEN1 (0.43) | MEN1KMT2AAOX1 | |
| SCHEMBL17489213 | 0.74 | MEN1 (0.53) | MEN1KMT2AAOX1NPSR1 | |
| SCHEMBL777550 | 0.74 | MEN1 (0.53) | MEN1KMT2AAOX1NPSR1 | |
| SCHEMBL10452383 | 0.73 | CETP (0.51) | MEN1KMT2AAOX1CETPNPSR1 | |
| SCHEMBL11315124 | 0.72 | MEN1 (0.45) | MEN1KMT2AAOX1CETPNPSR1 | |
| SCHEMBL5491426 | 0.72 | MEN1 (0.51) | MEN1KMT2AAOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922866-A | REACTING A TRIALKYLSILYL HALIDE WITH A 1,2-AMIDE SUBSTITUTED BENZENE DERIVATIVE IN THE PRESENCE OF A BASE; USE AS PHARMACEUTICALS OR INTERMEDIATES FOR SYNTHESIS THEREOF, SUCH AS ANTIDIABETIC DRUGS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1999-07-13 | — | — | US | disclosed |