Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8486547 | 0.96 | MEN1 (0.42) | MEN1KMT2AHIF1ACA2AOX1 | |
| SCHEMBL27537966 | 0.95 | MEN1 (0.41) | MEN1KMT2AHIF1ACA2AOX1 | |
| SCHEMBL8483774 | 0.92 | MEN1 (0.53) | MEN1KMT2ACA2AOX1 | |
| SCHEMBL8412588 | 0.90 | MEN1 (0.49) | MEN1KMT2AHIF1AAOX1 | |
| SCHEMBL8484070 | 0.85 | AOX1 (0.51) | MEN1KMT2AHIF1ACA2AOX1 | |
| SCHEMBL8487370 | 0.84 | CETP (0.49) | MEN1KMT2A | |
| SCHEMBL8483591 | 0.79 | MEN1 (0.42) | MEN1KMT2ACA2AOX1 | |
| SCHEMBL11783930 | 0.79 | MEN1 (0.50) | MEN1KMT2AHIF1AAOX1 | |
| SCHEMBL6769527 | 0.79 | CYP3A4 (0.42) | — | |
| SCHEMBL777550 | 0.79 | MEN1 (0.53) | MEN1KMT2AHIF1ACA2AOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1090621-C | Process for preparing quinazolin-4-one derivatives | OTSUKA PHARMA CO LTD (JP) | 2002-09-11 | — | — | CN | disclosed |
| US-5922866-A | REACTING A TRIALKYLSILYL HALIDE WITH A 1,2-AMIDE SUBSTITUTED BENZENE DERIVATIVE IN THE PRESENCE OF A BASE; USE AS PHARMACEUTICALS OR INTERMEDIATES FOR SYNTHESIS THEREOF, SUCH AS ANTIDIABETIC DRUGS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1999-07-13 | — | — | US | disclosed |
| CN-1193967-A | Process for producing quinazoline-4-one derivatives | OTSUKA PHARMA CO LTD (US) | 1998-09-23 | — | — | CN | disclosed |