Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL634085 | 0.88 | ALDH1A1 (0.79) | ALDH1A1LMNAMAPTSMN1; SMN2HPGD | |
| SCHEMBL7895365 | 0.87 | MEN1 (0.54) | ALDH1A1LMNAMAPTSMN1; SMN2HPGD | |
| SCHEMBL7802270 | 0.85 | FLT1 (0.54) | ALDH1A1MAPTSMN1; SMN2CA1CA2 | |
| SCHEMBL7811320 | 0.85 | ALDH1A1 (0.65) | ALDH1A1LMNAMAPTSMN1; SMN2CA1 | |
| SCHEMBL7814081 | 0.85 | KAT6A (0.49) | ALDH1A1LMNAMAPTSMN1; SMN2HPGD | |
| SCHEMBL7807017 | 0.81 | FLT1 (0.50) | ALDH1A1LMNAMAPTSMN1; SMN2HPGD | |
| SCHEMBL7810601 | 0.81 | HDAC1 (0.47) | ALDH1A1LMNAMAPTSMN1; SMN2HPGD | |
| SCHEMBL7807045 | 0.81 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTSMN1; SMN2HPGD | |
| SCHEMBL3716571 | 0.81 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPTSMN1; SMN2HPGD | |
| SCHEMBL3643243 | 0.81 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPTSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972950-A | ANTIINFLAMMATORY AND ANALGESIC AGENT | LABORATORIES UPSA (FR) | 1999-10-26 | — | — | US | disclosed |
| WO-1998015528-A1 | NOVEL DIARYLMETHYLENE DERIVATIVES, METHOD FOR PREPARING AND THERAPEUTIC USES THEREOF | LABORATOIRES UPSA (FR) | 1998-04-16 | — | — | WO | disclosed |