SCHEMBL8486602 — predicted protein targets

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	FNTA	P49354	17/20	0.39

▸	FNTB	P49356	17/20	0.39

▸	PGGT1B	P53609	13/20	0.39

▸	CYP11B1	P15538	2/20	0.39

▸	CYP11B2	P19099	2/20	0.39

▸	KCNH2	Q12809	2/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8486598	1.00	FNTA (0.39)	FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL8499040	0.94	FNTA (0.41)	FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL8486074	0.92	CYP11B1 (0.41)	FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL8480737	0.92	FNTA (0.42)	FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL8480741	0.92	FNTA (0.42)	FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL8498220	0.91	CYP11B1 (0.42)	FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL8501176	0.90	CYP11B1 (0.40)	FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL8584259	0.90	CYP11B1 (0.41)	FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL8492840	0.90	FNTA (0.40)	FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL8505999	0.90	FNTA (0.40)	FNTAFNTBPGGT1BCYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1999012912-A1	THIOUREA DERIVATIVES OR NON-TOXIC SALTS THEREOF FOR INHIBITNG RAS-TRANSFORMED CELL GROWTH	YUHAN CORPORATION (KR)	1999-03-18	—	—	WO	disclosed