Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | IDH2 | P48735 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 2/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489178 | 0.93 | MAPT (0.45) | NPSR1RAB9AMAPTNPC1MEN1 | |
| SCHEMBL8487714 | 0.92 | NPSR1 (0.44) | NPSR1RAB9AMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL8487927 | 0.90 | SMN1; SMN2 (0.48) | NPSR1RAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL8486154 | 0.90 | NPC1 (0.47) | NPSR1RAB9AMAPTNPC1MEN1 | |
| SCHEMBL8490061 | 0.89 | MAPT (0.44) | NPSR1RAB9AMAPTNPC1MEN1 | |
| SCHEMBL8486950 | 0.89 | KMT2A (0.48) | RAB9AMAPTNPC1MEN1KMT2A | |
| SCHEMBL8490721 | 0.88 | TRPV1 (0.43) | NPSR1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL8490225 | 0.87 | TYK2 (0.41) | NPSR1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL8487940 | 0.87 | HTT (0.52) | NPSR1RAB9AMAPTNPC1MEN1 | |
| SCHEMBL8489049 | 0.87 | TYK2 (0.39) | NPSR1RAB9AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999021835-A1 | QUINOLINE DERIVATIVES AS H+-ATPase INHIBITORS AND AS BONE RESORPTION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-05-06 | — | — | WO | disclosed |