Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | TYK2 | P29597 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8486703 | 0.93 | NPSR1 (0.46) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL8486950 | 0.92 | KMT2A (0.48) | MAPTKMT2AMEN1TYK2SMN1; SMN2 | |
| SCHEMBL8489650 | 0.91 | MAPT (0.41) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL8490721 | 0.91 | TRPV1 (0.43) | KMT2AMEN1LMNANPSR1TYK2 | |
| SCHEMBL8487714 | 0.91 | NPSR1 (0.44) | MAPTKMT2ANPSR1TYK2SMN1; SMN2 | |
| SCHEMBL8486154 | 0.91 | NPC1 (0.47) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL8487940 | 0.90 | HTT (0.52) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL8489174 | 0.89 | TRPV1 (0.42) | LMNANPSR1TYK2POLBJAK2 | |
| SCHEMBL8487927 | 0.89 | SMN1; SMN2 (0.48) | MAPTNPSR1SMN1; SMN2NPC1POLB | |
| SCHEMBL8486434 | 0.89 | SMN1; SMN2 (0.47) | MAPTKMT2AMEN1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999021835-A1 | QUINOLINE DERIVATIVES AS H+-ATPase INHIBITORS AND AS BONE RESORPTION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-05-06 | — | — | WO | disclosed |