Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.52 |
| ▸ | CDK8 | P49336 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5033492 | 0.95 | PTGER4 (0.55) | CCNCCDK8PTGER4PTGER3PTGER1 | |
| SCHEMBL10814335 | 0.95 | PTGER4 (0.54) | CCNCCDK8PTGER4PTGER3PTGER1 | |
| SCHEMBL31408195 | 0.89 | PTGER1 (0.48) | PTGER4PTGER3PTGER1PTGER2FFAR4 | |
| SCHEMBL9362082 | 0.89 | PTGER1 (0.48) | PTGER4PTGER3PTGER1PTGER2FFAR4 | |
| SCHEMBL12646541 | 0.84 | PTPN1 (0.55) | PTPN1FFAR4FFAR1TDP1CYP4F2 | |
| SCHEMBL27773458 | 0.84 | POLB (0.50) | CCNCCDK8PTPN1KMT2AKDM4E | |
| SCHEMBL28321278 | 0.83 | ACLY (0.48) | KMT2ACYP4F2CYP4A11 | |
| SCHEMBL6503486 | 0.83 | PTGER4 (0.46) | CCNCCDK8PTGER4PTGER3PTGER1 | |
| SCHEMBL12646545 | 0.82 | FFAR1 (0.52) | CCNCCDK8PTGER4PTGER3PTGER1 | |
| SCHEMBL29174148 | 0.82 | PTGER1 (0.44) | CCNCCDK8PTGER4PTGER3PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990158-A | EXTRACELLULAR MATRIX METALLOPROTEINASES INHIBITORS; ORAL ADMINISTRATION; BIOAVAILABILITY; E.G.,N-(2-(2'-(5-METHYL-2-OXO-1,3-DIOXOL-4-YL)METHYLENE-OXY-2'-OXO-ETHYL)-5 -(4-METH-OXYPHENYL)OXY)PENTANOYL)PHENYLALANINE N-METHYLAMIDE | KOTOBUKI SEIYAKU CO., LTD. (JP) | 1999-11-23 | — | — | US | disclosed |