Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8485663 | 0.85 | TOP2A (0.46) | TOP2A | |
| SCHEMBL10812073 | 0.85 | TOP2A (0.49) | TOP2A | |
| SCHEMBL8486344 | 0.84 | TOP2A (0.40) | TOP2A | |
| SCHEMBL8483473 | 0.84 | TOP2A (0.42) | TOP2A | |
| SCHEMBL8716418 | 0.83 | — | — | |
| SCHEMBL8487520 | 0.83 | — | — | |
| SCHEMBL8486920 | 0.80 | TOP2A (0.43) | TOP2A | |
| SCHEMBL8487998 | 0.80 | TOP2A (0.43) | TOP2A | |
| SCHEMBL8483875 | 0.79 | KDM1A (0.34) | TOP2A | |
| SCHEMBL8485606 | 0.77 | TOP2A (0.42) | TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935969-A | Pyrido-thiopyrandoinazoles with antitumor activity | UNIVERSITY OF VERMONT (US) | 1999-08-10 | — | — | US | disclosed |
| EP-0837861-A1 | NEW PYRIDO-THIOPYRANOINDAZOLES WITH ANTITUMOR ACTIVITY | THE UNIVERSITY OF VERMONT (US) | 1998-04-29 | — | — | EP | disclosed |
| WO-1997002267-A1 | NEW PYRIDO-THIOPYRANOINDAZOLES WITH ANTITUMOR ACTIVITY | UNIVERSITY OF VERMONT (US) | 1997-01-23 | — | — | WO | disclosed |