Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 6/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | F13A1 | P00488 | 3/20 | 0.50 |
| ▸ | TGM2 | P21980 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8339724 | 1.00 | EPHX1 (0.62) | EPHX1TSHRF13A1TGM2CYP2C19 | |
| SCHEMBL8376293 | 1.00 | EPHX1 (0.62) | EPHX1TSHRF13A1TGM2CYP2C19 | |
| SCHEMBL1692473 | 0.82 | EPHX1 (0.67) | EPHX1TSHRCYP2C19MEN1TP53 | |
| SCHEMBL5598863 | 0.82 | EPHX1 (0.67) | EPHX1TSHRF13A1TGM2CYP2C19 | |
| SCHEMBL3343090 | 0.82 | EPHX1 (0.67) | EPHX1TSHRCYP2C19MEN1TP53 | |
| SCHEMBL14571889 | 0.82 | EPHX1 (0.67) | EPHX1TSHRF13A1TGM2CYP2C19 | |
| SCHEMBL6689012 | 0.82 | EPHX1 (0.67) | EPHX1TSHRCYP2C19MEN1TP53 | |
| SCHEMBL5598408 | 0.82 | EPHX1 (0.67) | EPHX1TSHRF13A1TGM2CYP2C19 | |
| SCHEMBL5598404 | 0.82 | EPHX1 (0.67) | EPHX1TSHRF13A1TGM2CYP2C19 | |
| SCHEMBL4071198 | 0.82 | EPHX1 (0.67) | EPHX1TSHRCYP2C19MEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883264-A | SUBJECTING RACEMIC TRANS-3-PHENYLGLYCIDAMIDE COMPOUND TO OPTICAL RESOLUTION USING A MICROORGANISM HAVING ABILITY OF PREFERENTIALLY HYDROLYZING ONE OF (2S,3R) ISOMER OR (2R,3S) ISOMER THEREOF | TANABE SEIYAKU CO., LTD. (JP) | 1999-03-16 | — | — | US | disclosed |
| EP-0795609-A2 | Process for preparing optically active trans-3-phenylglycidamide compounds | TANABE SEIYAKU CO., LTD. (JP) | 1997-09-17 | — | — | EP | disclosed |