Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | FABP7 | O15540 | 3/20 | 0.39 |
| ▸ | FABP3 | P05413 | 3/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | HTR1B | P28222 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6865702 | 0.89 | HTR1B (0.43) | ALDH1A1KDM4EHPGDTDP1KCNA3 | |
| SCHEMBL674709 | 0.85 | MAPK1 (0.47) | ALDH1A1KDM4EHPGDTDP1SMN1; SMN2 | |
| SCHEMBL31556331 | 0.85 | HTR1B (0.48) | ALDH1A1KDM4EHPGDTDP1KCNA3 | |
| SCHEMBL1449787 | 0.85 | HTR1B (0.48) | ALDH1A1KDM4EHPGDTDP1KCNA3 | |
| SCHEMBL13839427 | 0.82 | MAPT (0.33) | TNFALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL8116632 | 0.80 | NCOA1 (0.49) | TNFALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL10929913 | 0.80 | KCNA3 (0.51) | ALDH1A1KDM4EHPGDTDP1KCNA3 | |
| SCHEMBL11250659 | 0.78 | NCOA1 (0.46) | ALDH1A1HPGDTDP1L3MBTL1HSD17B10 | |
| SCHEMBL8487523 | 0.77 | NCOA1 (0.42) | ALDH1A1KDM4ETDP1MEN1KMT2A | |
| SCHEMBL11121722 | 0.76 | ESR1 (0.38) | MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962744-A | USING CATALYST COMPLEX CONTAINING TRANSITION METAL AND PHOSPHITE LIGAND | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1999-10-05 | — | — | US | claimed |
| US-5962744-A | USING CATALYST COMPLEX CONTAINING TRANSITION METAL AND PHOSPHITE LIGAND | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1999-10-05 | — | — | US | disclosed |