Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31556331 | 1.00 | HTR1B (0.48) | HTR1BALDH1A1KDM4ETDP1KCNA3 | |
| SCHEMBL6865702 | 0.92 | HTR1B (0.43) | HTR1BALDH1A1KDM4ETDP1KCNA3 | |
| SCHEMBL10929913 | 0.90 | KCNA3 (0.51) | HTR1BALDH1A1KDM4ETDP1KCNA3 | |
| SCHEMBL21381123 | 0.88 | KCNA3 (0.46) | HTR1BALDH1A1KDM4ETDP1KCNA3 | |
| SCHEMBL8956096 | 0.88 | ALDH1A1 (0.52) | HTR1BALDH1A1KDM4ETDP1KCNA3 | |
| SCHEMBL9328250 | 0.87 | HTR1B (0.43) | HTR1BALDH1A1KDM4ETDP1KCNA3 | |
| SCHEMBL1604278 | 0.87 | HTR1B (0.43) | HTR1BALDH1A1KDM4ETDP1KCNA3 | |
| SCHEMBL13839483 | 0.85 | CDC25B (0.50) | ALDH1A1KDM4ETDP1HPGDHSD17B10 | |
| SCHEMBL8487339 | 0.85 | TNF (0.41) | HTR1BALDH1A1KDM4ETDP1KCNA3 | |
| SCHEMBL13839460 | 0.84 | HTR1B (0.38) | HTR1BALDH1A1KDM4ETDP1KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 559 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2481760-B1 | INITIATOR SYSTEM FOR CATIONIC POLYMERIZATION AND POLYMERIZATION METHOD USING SAME | CHINA PETROLEUM & CHEM CORP (CN) | 2021-05-05 | — | — | EP | claimed |
| US-9678225-B1 | High-symmetry organic scintillator systems | NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC (US) | 2017-06-13 | — | — | US | claimed |
| US-7220884-B2 | Hydroaminomethylation of olefins | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2007-05-22 | — | — | US | claimed |
| EP-1713757-A2 | HYDROAMINOMETHYLATION OF OLEFINS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2006-10-25 | — | — | EP | claimed |
| EP-1313823-A4 | PHOSPHITE COKE INHIBITORS FOR EDC-VCM FURNACES | ONDEO NALCO ENERGY SERV LP (US) | 2006-04-05 | — | — | EP | claimed |
| US-20050215825-A1 | Hydroaminomethylation of olefins | UNION CARBIDE CORPORATION | 2005-09-29 | — | — | US | claimed |
| WO-2005077884-A2 | HYDROAMINOMETHYLATION OF OLEFINS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2005-08-25 | — | — | WO | claimed |
| US-20050084204-A1 | Digital dyes based on electrochemical redox reactions | HEWLETT-PACKARD DEVELOPMENT COMPANY L.P. | 2005-04-21 | — | — | US | claimed |
| JP-2004506655-A | — | — | 2004-03-04 | — | — | JP | claimed |
| EP-1313823-A1 | PHOSPHITE COKE INHIBITORS FOR EDC-VCM FURNACES | ONDEO NALCO ENERGY SERVICES, L.P. (US) | 2003-05-28 | — | — | EP | claimed |
| US-6368494-B1 | ANTIDEPOSIT AGENTS | NALCO/EXXON ENERGY CHEMICALS, L.P. | 2002-04-09 | — | — | US | claimed |
| WO-2002014454-A1 | PHOSPHITE COKE INHIBITORS FOR EDC-VCM FURNACES | ONDEO NALCO ENERGY SERVICES, L.P. (US) | 2002-02-21 | — | — | WO | claimed |
| WO-2001051441-A1 | HYDROFORMYLATION METHOD FOR MAKING ALDEHYDES FROM STERICALLY HINDERED OLEFINS | EASTMAN CHEMICAL COMPANY (US) | 2001-07-19 | — | — | WO | claimed |
| US-5858907-A | Nickel phosphite catalysts | MAXDEM, INCORPORATED (US) | 1999-01-12 | — | — | US | claimed |
| WO-1996039455-A1 | NICKEL PHOSPHITE CATALYSTS | MAXDEM INCORPORATED (US) | 1996-12-12 | — | — | WO | claimed |
| US-4400547-A | LIGANDIZING REACTOR EFFLUENT TO PREVENT CATALYST LOSS THROUGH PLATING | EASTMAN KODAK COMPANY (US) | 1983-08-23 | — | — | US | claimed |
| US-4195042-A | Rhodium hydroformylation catalyst | PHILLIPS PETROLEUM COMPANY (US) | 1980-03-25 | — | — | US | claimed |
| US-3956177-A | Rhodium hydroformylation catalyst | PHILLIPS PETROLEUM COMPANY (US) | 1976-05-11 | — | — | US | claimed |
| US-6444863-B1 | — | — | None | — | — | US | disclosed |
| US-3944603-A | AND PROPIONIC ANHYDRIDE FROM ETHYLENE AND CARBON MONOXIDE, IRIDIUM COMPLEX CATALYST | MONSANTO COMPANY (US) | 1976-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215825-A1 | Hydroaminomethylation of olefins | HRH2, HRH4, HRH1 | HTR1B 610/4885ALDH1A1 1249/4885KDM4E 3389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.