Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 4/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.36 |
| ▸ | MTOR | P42345 | 3/20 | 0.36 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766710 | 1.00 | CHRM4 (0.37) | CHRM4PIK3CAMTORPIM1IRAK4 | |
| SCHEMBL7198151 | 0.90 | IRAK4 (0.37) | CHRM4IRAK4KDM4EBTKCYP3A4 | |
| SCHEMBL8120612 | 0.90 | IRAK4 (0.37) | CHRM4IRAK4KDM4EBTKCYP3A4 | |
| SCHEMBL8484462 | 0.88 | IRAK4 (0.34) | CHRM4IRAK4KDM4EBTKCYP3A4 | |
| SCHEMBL8487365 | 0.84 | BTK (0.42) | IRAK4KDM4EBTKFLT3 | |
| SCHEMBL8486785 | 0.84 | BTK (0.42) | IRAK4KDM4EBTKFLT3 | |
| SCHEMBL8483434 | 0.82 | BTK (0.43) | CHRM4PIK3CAMTORIRAK4KDM4E | |
| SCHEMBL8483437 | 0.82 | BTK (0.43) | CHRM4PIK3CAMTORIRAK4KDM4E | |
| SCHEMBL8490025 | 0.81 | IRAK4 (0.45) | CHRM4IRAK4KDM4EBTKCYP3A4 | |
| SCHEMBL8488399 | 0.81 | IRAK4 (0.39) | CHRM4IRAK4KDM4EBTKCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889012-A | INSECTICIDE, ACARICIDES, FUNGICIDES | HOECHST-SCHERING AGREVO GMBH (DE) | 1999-03-30 | — | — | US | disclosed |
| EP-0787128-A1 | SUBSTITUTED CYCLOALKYLAMINO AND CYCLOALKOXY HETEROCYCLES, PROCESS FOR PREPARING THE SAME AND THEIR USE AS PESTICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1997-08-06 | — | — | EP | disclosed |
| WO-1996011913-A1 | SUBSTITUTED CYCLOALKYLAMINO AND CYCLOALKOXY HETEROCYCLES, PROCESS FOR PREPARING THE SAME AND THEIR USE AS PESTICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1996-04-25 | — | — | WO | disclosed |