Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | CCNK | O75909 | 3/20 | 0.43 |
| ▸ | CDK12 | Q9NYV4 | 3/20 | 0.43 |
| ▸ | KDM5A | P29375 | 4/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3308187 | 0.89 | F10 (0.56) | F10CCNKCDK12KDM5AMCHR1 | |
| SCHEMBL3300888 | 0.89 | ALDH1A1 (0.45) | F10CCNKCDK12KDM5AHDAC6 | |
| SCHEMBL3306427 | 0.89 | F10 (0.56) | F10CCNKCDK12KDM5AMCHR1 | |
| SCHEMBL3305721 | 0.89 | F10 (0.56) | F10CCNKCDK12KDM5AMCHR1 | |
| SCHEMBL3311836 | 0.86 | F10 (0.42) | F10CCNKCDK12KDM5AHDAC6 | |
| SCHEMBL3310161 | 0.86 | F10 (0.57) | F10CCNKCDK12KDM5AMCHR1 | |
| SCHEMBL3312666 | 0.86 | F10 (0.57) | F10CCNKCDK12KDM5AMCHR1 | |
| SCHEMBL3306214 | 0.86 | ALDH1A1 (0.47) | F10CCNKCDK12KDM5AHDAC6 | |
| SCHEMBL3307351 | 0.86 | F10 (0.57) | F10CCNKCDK12KDM5AMCHR1 | |
| SCHEMBL3309468 | 0.86 | F10 (0.57) | F10CCNKCDK12KDM5AMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1975165-A1 | Substituted pyrrolidinamides, their production and utilisation as medicine | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2008-10-01 | — | — | EP | disclosed |