Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | F9 | P00740 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524139 | 0.92 | SMN1; SMN2 (0.41) | HSP90AA1MAPTHTTSMN1; SMN2F9 | |
| SCHEMBL8487594 | 0.91 | SMN1; SMN2 (0.40) | HSP90AA1MAPTHTTSMN1; SMN2F9 | |
| SCHEMBL8524135 | 0.89 | SMN1; SMN2 (0.39) | HSP90AA1MAPTHTTSMN1; SMN2F9 | |
| SCHEMBL8525429 | 0.88 | NR1H4 (0.40) | HSP90AA1MAPTHTTSMN1; SMN2F9 | |
| SCHEMBL8524453 | 0.88 | SMN1; SMN2 (0.38) | HSP90AA1MAPTHTTSMN1; SMN2F9 | |
| SCHEMBL8488306 | 0.88 | SMN1; SMN2 (0.38) | HSP90AA1MAPTHTTSMN1; SMN2F9 | |
| SCHEMBL8525742 | 0.86 | SMN1; SMN2 (0.37) | HSP90AA1MAPTHTTSMN1; SMN2MEN1 | |
| SCHEMBL8490794 | 0.86 | AVPR2 (0.39) | SMN1; SMN2F9NR1H4 | |
| SCHEMBL8490972 | 0.86 | KDM4E (0.38) | MAPTF9MEN1KMT2ANR1H4 | |
| SCHEMBL8525290 | 0.86 | HCRTR2 (0.43) | HSP90AA1NR1H4NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999003856-A1 | 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |