Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8492222 | 0.92 | ALDH1A1 (0.42) | KDM4EALDH1A1USP2ALOX15CASP1 | |
| SCHEMBL8492214 | 0.89 | KDM4E (0.37) | KDM4EALDH1A1USP2ALOX15CASP1 | |
| SCHEMBL8490513 | 0.88 | NOTUM (0.38) | KDM4EALDH1A1ALOX15NOTUMHPGD | |
| SCHEMBL8487558 | 0.86 | HSP90AA1 (0.41) | MEN1KMT2ANOTUMMAPTF9 | |
| SCHEMBL8490794 | 0.84 | AVPR2 (0.39) | KDM4EALDH1A1ALOX15POLBHPGD | |
| SCHEMBL8525290 | 0.84 | HCRTR2 (0.43) | ALDH1A1NOTUMNR1H4 | |
| SCHEMBL8494706 | 0.82 | KDM4E (0.39) | KDM4EALDH1A1USP2ALOX15CASP1 | |
| SCHEMBL8525868 | 0.82 | LMNA (0.37) | KDM4EALDH1A1USP2ALOX15CASP1 | |
| SCHEMBL8488638 | 0.82 | HTT (0.44) | ALDH1A1MEN1KMT2AHPGDLMNA | |
| SCHEMBL8488359 | 0.80 | ALDH1A1 (0.37) | KDM4EALDH1A1HPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999003856-A1 | 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |