SCHEMBL8487567

SCHEMBL8487567

COc1ccccc1SCl.Sc1ccccc1Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
CA7 P43166 2/20 0.39
CA9 Q16790 2/20 0.39
CA12 O43570 1/20 0.39
CA4 P22748 1/20 0.39
CA14 Q9ULX7 1/20 0.39
L3MBTL1 Q9Y468 5/20 0.38
TUBB4A P04350 1/20 0.37
TUBB P07437 1/20 0.37
TUBA3C P0DPH7 1/20 0.37
IDO1 P14902 1/20 0.37
TUBA1B P68363 1/20 0.37
TUBA4A P68366 1/20 0.37
TUBB4B P68371 1/20 0.37
TUBB3 Q13509 1/20 0.37
TUBB2A Q13885 1/20 0.37
TUBB8 Q3ZCM7 1/20 0.37
TUBA3E Q6PEY2 1/20 0.37
TUBA1A Q71U36 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1712860 0.84 CA1 (0.55) CA1CA2CA7CA9CA12
Diphenylsulfane SCHEMBL9746860 0.74 CA1 (0.43) CA1CA2CA7CA9CA12
SCHEMBL8487569 0.71 MAPT (0.40) L3MBTL1IDO1KMT2AHAO1MAPT
SCHEMBL48322 0.71
SCHEMBL29565928 0.71
SCHEMBL8487860 0.69 KDM4E (0.30) IDO1RAB9ANPC1SMN1; SMN2ALDH1A1
SCHEMBL12541 0.69
SCHEMBL29518025 0.69
SCHEMBL8179 0.69
SCHEMBL28061440 0.69 CA1 (0.63) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5932731-A HYDROLYZING A HETEROAROMATIC HALOGENATED METHYL SULFIDE IN PRESENCE OF AN ACID SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1999-08-03 US disclosed
US-5741933-A HYDROLYSIS; OXIDATION SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1998-04-21 US disclosed