SCHEMBL8487569

SCHEMBL8487569

CSc1ccccc1Cl.Sc1ccccc1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.40
KMT2A Q03164 3/20 0.40
MEN1 O00255 2/20 0.40
SMN1; SMN2 Q16637 5/20 0.39
ALDH1A1 P00352 5/20 0.39
KDM4E B2RXH2 5/20 0.38
NPSR1 Q6W5P4 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
RXFP1 Q9HBX9 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
LMNA P02545 3/20 0.36
TSHR P16473 1/20 0.36
HPGD P15428 4/20 0.36
STK10 O94804 1/20 0.35
SLK Q9H2G2 1/20 0.35
NPC1 O15118 4/20 0.34
RAB9A P51151 4/20 0.34
HAO1 Q9UJM8 1/20 0.33
CYP1A1 P04798 1/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL255293 0.87
SCHEMBL31336772 0.87
SCHEMBL48322 0.79
SCHEMBL29565928 0.79
SCHEMBL8488464 0.78 LMNA (0.35) MAPTALDH1A1KDM4ENPSR1L3MBTL1
SCHEMBL4652786 0.77
Hydrogen Sulfide SCHEMBL27747337 0.77 TSHR (0.53) MAPTALDH1A1LMNATSHRCYP1A2
SCHEMBL28074146 0.77
Hydrochloric Acid SCHEMBL7262825 0.77
Hydrogen Sulfide SCHEMBL28264855 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5932731-A HYDROLYZING A HETEROAROMATIC HALOGENATED METHYL SULFIDE IN PRESENCE OF AN ACID SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1999-08-03 US disclosed
US-5741933-A HYDROLYSIS; OXIDATION SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1998-04-21 US disclosed