Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8483893 | 1.00 | PPARD (0.38) | PPARDENPP2S1PR2S1PR1S1PR3 | |
| SCHEMBL8486626 | 0.98 | PPARD (0.39) | PPARDENPP2 | |
| SCHEMBL6898444 | 0.87 | PPARD (0.42) | PPARD | |
| SCHEMBL14890455 | 0.84 | CETP (0.50) | — | |
| SCHEMBL7331812 | 0.82 | CETP (0.47) | — | |
| SCHEMBL8483551 | 0.80 | PSEN1 (0.40) | PPARDS1PR2S1PR1S1PR3 | |
| SCHEMBL8487838 | 0.80 | PSEN1 (0.40) | PPARDS1PR2S1PR1S1PR3 | |
| SCHEMBL11301094 | 0.79 | KCNH2 (0.42) | — | |
| SCHEMBL8486224 | 0.78 | PSEN1 (0.38) | PPARD | |
| SCHEMBL8658558 | 0.77 | CETP (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1090621-C | Process for preparing quinazolin-4-one derivatives | OTSUKA PHARMA CO LTD (JP) | 2002-09-11 | — | — | CN | disclosed |
| US-5922866-A | REACTING A TRIALKYLSILYL HALIDE WITH A 1,2-AMIDE SUBSTITUTED BENZENE DERIVATIVE IN THE PRESENCE OF A BASE; USE AS PHARMACEUTICALS OR INTERMEDIATES FOR SYNTHESIS THEREOF, SUCH AS ANTIDIABETIC DRUGS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1999-07-13 | — | — | US | disclosed |
| CN-1193967-A | Process for producing quinazoline-4-one derivatives | OTSUKA PHARMA CO LTD (US) | 1998-09-23 | — | — | CN | disclosed |