SCHEMBL8658558

SCHEMBL8658558

CCOP(=O)(CCCc1ccccc1)OCC

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CETP P11597 1/20 0.45
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7331812 0.95 CETP (0.47) CETPTSHR
SCHEMBL14890455 0.93 CETP (0.50) CETPTSHR
SCHEMBL5248630 0.89 CETP (0.47) CETPTSHR
SCHEMBL1835123 0.83 TAAR1 (0.42)
SCHEMBL11795292 0.83 MAOB (0.43)
SCHEMBL1833138 0.83 FDPS (0.43)
SCHEMBL9602529 0.83 HRH1 (0.41) TSHR
SCHEMBL3486531 0.82 RARB (0.54)
SCHEMBL10936592 0.82 CETP (0.46) CETPTSHR
SCHEMBL27991950 0.81 TSHR (0.47) CETPTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5852198-A Wittig reagents and method for preparing α,β-unsaturated phosphonates MEDICHEM RESEARCH, INC. (US) 1998-12-22 US disclosed
WO-1997036909-A1 WITTIG REAGENTS AND METHOD FOR PREPARING α,β-UNSATURATED PHOSPHONATES MEDICHEM RESEARCH, INC. (US) 1997-10-09 WO disclosed