Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ADA | P00813 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22664844 | 0.81 | NR1I2 (0.43) | KCNH2NR1I2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22639542 | 0.77 | TAS1R3 (0.36) | KCNH2SMN1; SMN2 | |
| SCHEMBL18671786 | 0.76 | NR1I2 (0.36) | KCNH2NR1I2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18671760 | 0.76 | NR1I2 (0.36) | KCNH2NR1I2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6683039 | 0.76 | ADA (0.41) | KCNH2CYP1A2CYP2C9CYP2C19NR1I2 | |
| SCHEMBL19513926 | 0.76 | ADA (0.41) | KCNH2CYP1A2CYP2C9CYP2C19NR1I2 | |
| SCHEMBL8487674 | 0.75 | POLB (0.39) | NR1I2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28211074 | 0.74 | ADA (0.42) | KCNH2CYP1A2CYP2C9CYP2C19NR1I2 | |
| SCHEMBL21423075 | 0.74 | MEN1 (0.41) | KCNH2NR1I2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29745034 | 0.73 | CYP1A2 (0.36) | CYP1A2CYP2C9CYP2C19NR1I2TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952324-A | BACTERICIDES AGAINST A NUMBER OF HUMAN AND VETERINARY PATHOGENS, INCLUDING GRAMPOSITIVE AEROBIC BACTERIA SUCH AS STAPHYLOCOCCI, STREPTOCOCCI, ENTEROCOCCI AND ANAEROBIC ORGANISMS SUCH AS BACTEROIDES, CLOSTRIDIA AND MYCOBACTERIUM | PHARMACIA & UPJOHN COMPANY (US) | 1999-09-14 | — | — | US | disclosed |