SCHEMBL848807

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL848805	1.00	SLC1A3 (0.38)	SLC1A3SLC1A2SLC1A1IDH1PTH1R
	SCHEMBL848806	1.00	SLC1A3 (0.38)	SLC1A3SLC1A2SLC1A1IDH1PTH1R
	SCHEMBL849734	0.89	PTH1R (0.42)	IDH1PTH1REPHX2KDM4EMEN1
	SCHEMBL849733	0.89	PTH1R (0.42)	IDH1PTH1REPHX2KDM4EMEN1
	SCHEMBL13555066	0.88	EGFR (0.38)	IDH1
	SCHEMBL16359056	0.88	SLC1A3 (0.39)	SLC1A3SLC1A2SLC1A1IDH1MEN1
	SCHEMBL850075	0.85	PTH1R (0.51)	SLC1A3SLC1A2SLC1A1IDH1PTH1R
	SCHEMBL850074	0.85	PTH1R (0.51)	SLC1A3SLC1A2SLC1A1IDH1PTH1R
	SCHEMBL848691	0.83	PTH1R (0.34)	PTH1R
	SCHEMBL13552105	0.82	IP6K1 (0.40)	PTH1RKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.