Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | CDK4 | P11802 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | CDK7 | P50613 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.33 |
| ▸ | PDE9A | O76083 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 3/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6613792 | 0.82 | CDK4 (0.40) | HCRTR2HCRTR1MKNK2HRH4CDK4 | |
| SCHEMBL9057676 | 0.75 | L3MBTL1 (0.43) | HRH4 | |
| SCHEMBL5663343 | 0.72 | PDE9A (0.47) | MKNK2PDE9A | |
| SCHEMBL29586318 | 0.71 | PDE9A (0.40) | HCRTR2HCRTR1MKNK2HRH4PDE9A | |
| SCHEMBL5463861 | 0.70 | HRH4 (0.51) | HRH4CDK2CDK9HTR3A | |
| SCHEMBL2320140 | 0.68 | MKNK2 (0.47) | MKNK2PDE9AACACB | |
| SCHEMBL30211008 | 0.68 | MKNK2 (0.47) | MKNK2PDE9AACACB | |
| SCHEMBL2320138 | 0.68 | MKNK2 (0.47) | MKNK2PDE9AACACB | |
| SCHEMBL1177568 | 0.66 | SLC6A2 (0.52) | PDE9AHTR3A | |
| SCHEMBL1177572 | 0.66 | SLC6A2 (0.52) | PDE9AHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889012-A | INSECTICIDE, ACARICIDES, FUNGICIDES | HOECHST-SCHERING AGREVO GMBH (DE) | 1999-03-30 | — | — | US | disclosed |