Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 3/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | SMYD3 | Q9H7B4 | 11/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8608679 | 0.87 | STAT3 (0.46) | STAT3STAT1SMYD3RAB9ANPC1 | |
| SCHEMBL8607579 | 0.85 | SMYD3 (0.47) | STAT3STAT1SMYD3RAB9ANPC1 | |
| SCHEMBL8493741 | 0.84 | SMYD3 (0.45) | STAT3STAT1SMYD3RAB9ANPC1 | |
| SCHEMBL8887361 | 0.80 | DHODH (0.35) | MEN1KMT2A | |
| SCHEMBL8609002 | 0.77 | STAT3 (0.46) | STAT3STAT1SMYD3RAB9ANPC1 | |
| SCHEMBL8607164 | 0.77 | RAB9A (0.50) | STAT3STAT1SMYD3RAB9ANPC1 | |
| SCHEMBL8606609 | 0.76 | STAT3 (0.49) | STAT3STAT1SMYD3RAB9ANPC1 | |
| SCHEMBL8608712 | 0.74 | STAT1 (0.43) | STAT1SMYD3RAB9ANPC1ALDH1A1 | |
| SCHEMBL8389460 | 0.73 | MEN1 (0.49) | STAT3STAT1SMYD3RAB9ANPC1 | |
| SCHEMBL8387524 | 0.72 | RAB9A (0.50) | STAT3STAT1SMYD3RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859283-A | TERTIARY-BUTYL 3-CYCLOALKYL-3-OXOPROPIONATE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| US-5747424-A | HEATING AN AROMATIC DIKETONE WITH A SALT OF HYDROXYLAMINE IN A SOLVENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-05-05 | — | — | US | disclosed |