SCHEMBL848827

SCHEMBL848827

C=CCCC=C(CC)CC

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.43
ALDH1A1 P00352 2/20 0.39
BACE1 P56817 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL848348 0.85 TSHR (0.42) TSHRALDH1A1BACE1
SCHEMBL848349 0.85 TSHR (0.42) TSHRALDH1A1BACE1
SCHEMBL849065 0.84 TSHR (0.48) TSHRALDH1A1BACE1
SCHEMBL846849 0.84 TSHR (0.50) TSHRALDH1A1BACE1
SCHEMBL9645963 0.82 TSHR (0.54) TSHRALDH1A1BACE1
SCHEMBL28199948 0.82 TSHR (0.33) TSHRALDH1A1
SCHEMBL848477 0.82 TSHR (0.46) TSHRALDH1A1BACE1
SCHEMBL3730693 0.82 SQLE (0.36) TSHRALDH1A1
SCHEMBL848476 0.82 TSHR (0.46) TSHRALDH1A1BACE1
SCHEMBL847851 0.80 SQLE (0.48) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 339 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3882283-A1 ETHYLENE-COPOLYMERS AND CATALYST MIXTURE FOR MAKING ETHYLENE COPOLYMERS Arlanxeo Netherlands B.V. (NL) 2021-09-22 EP claimed
CN-105339394-B The catalyst mitigated in olefinic polymerization suppresses 埃克森美孚化学专利公司 2017-06-09 CN claimed
US-9382344-B2 Mitigation of catalyst inhibition in olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-07-05 US claimed
EP-3013867-A1 MITIGATION OF CATALYST INHIBITION IN OLEFIN POLYMERIZATION ExxonMobil Chemical Patents Inc. (US) 2016-05-04 EP claimed
CN-105339394-A Mitigation of catalyst inhibition in olefin polymerization EXXONMOBIL CHEM PATENTS INC 2016-02-17 CN claimed
WO-2014209813-A1 MITIGATION OF CATALYST INHIBITION IN OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-12-31 WO claimed
US-20140378732-A1 Mitigation of Catalyst Inhibition in Olefin Polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2014-12-25 US claimed
EP-1016689-B1 Olefin thermoplastic elastomer compositions MITSUI CHEMICALS INC (JP) 2007-03-07 EP claimed
EP-4119568-B1 NOVEL METALLOCENE COMPOUND, CATALYST COMPOSITION COMPRISING THE SAME, AND METHOD FOR PREPARING OLEFIN POLYMER USING THE SAME LG CHEMICAL LTD (KR) 2026-05-20 EP disclosed
US-12617881-B2 Metallocene compound, catalyst composition comprising the same, and method for preparing olefin polymer using the same LG CHEM, LTD. (KR) 2026-05-05 US disclosed
US-12559581-B2 Ethylene-copolymers and catalyst mixture for making ethylene copolymers ARLANXEO NETHERLANDS B.V. (NL) 2026-02-24 US disclosed
US-20250313041-A1 TIRE COMPOSITIONS COMPRISING FUNCTIONALIZED RUBBERS BASED ON ETHYLENE-COPOLYMERS ARLANXEO DEUTSCHLAND GMBH (DE) 2025-10-09 US disclosed
EP-4043500-B1 ETHYLENE·ALPHA-OLEFIN·NON-CONJUGATED POLYENE COPOLYMER, USE THEREOF, AND MANUFACTURING METHOD THEREOF MITSUI CHEMICALS INC (JP) 2025-08-13 EP disclosed
EP-4330297-B1 METAL COMPLEX CATALYST FOR THE POLYMERIZATION OF OLEFINS Arlanxeo Netherlands Bv (NL) 2025-07-30 EP disclosed
EP-0634427-A1 Higher alpha-olefin copolymer, process for the preparation of the same, rubber composition comprising the same, and rubber molded product comprising the same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-01-18 EP disclosed
US-5349020-A Olefin-diene copolymer and a second rubber MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-09-20 US disclosed
EP-0559218-A1 Vulcanizable rubber composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-09-08 EP disclosed
EP-0552798-A2 Higher alpha-olefin copolymer, process for the preparation of the same, vibration insulating rubber molded product, and process for the preparation of the rubber molded product MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-07-28 EP disclosed
US-5229463-A Blending, crosslinking propylene copolymerized with conjugated and non-connugated dienes, EPDM rubber and crystalline propylene polymer MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) 1993-07-20 US disclosed
EP-0486293-A2 Thermoplastic resin compositions having improved strength and method for producing them MITSUBISHI CHEMICAL CORPORATION (JP) 1992-05-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12617881-B2 Metallocene compound, catalyst composition comprising the same, and method for preparing olefin polymer using the same CNOT1, SMARCC1, CNOT7 TSHR 3144/4885ALDH1A1 1216/4885BACE1 1477/4885
US-12559581-B2 Ethylene-copolymers and catalyst mixture for making ethylene copolymers EEF1D, COG7, CCND1 TSHR 3104/4885ALDH1A1 3591/4885BACE1 4442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.