Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8483491 | 0.90 | TOP2A (0.32) | TOP2ATOP2B | |
| SCHEMBL8485118 | 0.86 | CYP2D6 (0.36) | TOP2ATOP2B | |
| SCHEMBL8488090 | 0.86 | TOP2A (0.32) | TOP2ATOP2B | |
| SCHEMBL8488003 | 0.84 | TOP2A (0.46) | TOP2ATOP2B | |
| SCHEMBL10923929 | 0.84 | NPY5R (0.35) | TOP2ATOP2B | |
| SCHEMBL8489718 | 0.83 | NQO1 (0.35) | — | |
| SCHEMBL8486920 | 0.83 | TOP2A (0.43) | TOP2ATOP2B | |
| SCHEMBL8716395 | 0.81 | TOP2A (0.35) | TOP2A | |
| SCHEMBL8487456 | 0.81 | DYRK1A (0.35) | TOP2ATOP2B | |
| SCHEMBL8486027 | 0.77 | TOP2A (0.32) | TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935969-A | Pyrido-thiopyrandoinazoles with antitumor activity | UNIVERSITY OF VERMONT (US) | 1999-08-10 | — | — | US | disclosed |