Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 4/20 | 0.34 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.31 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10925471 | 0.85 | TOP2A (0.39) | TOP2ATOP2B | |
| SCHEMBL8483491 | 0.84 | TOP2A (0.32) | TOP2ATOP2B | |
| SCHEMBL8488337 | 0.84 | TOP2A (0.30) | TOP2ATOP2B | |
| SCHEMBL10812739 | 0.83 | CYP1A2 (0.40) | TOP2ATOP2B | |
| SCHEMBL7488073 | 0.83 | TOP2A (0.50) | TOP2ATOP2B | |
| SCHEMBL8486027 | 0.83 | TOP2A (0.32) | TOP2A | |
| SCHEMBL10812073 | 0.82 | TOP2A (0.49) | NPY5RTOP2ATOP2B | |
| SCHEMBL10810510 | 0.82 | NQO1 (0.36) | TOP2ATOP2B | |
| Hydrochloric Acid SCHEMBL10925309 | 0.82 | TOP2A (0.49) | TOP2ATOP2B | |
| SCHEMBL8487520 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4518607-A | FUNGICIDES, BACXTERICIDES AND ANTIPROTOZOA AGENTS | SYNTEX (U.S.A.) INC. (US) | 1985-05-21 | — | — | US | disclosed |