SCHEMBL8488471

SCHEMBL8488471

CCC([O])CC(=O)N1CCOCC1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.48
TSHR P16473 3/20 0.47
POLB P06746 3/20 0.47
LMNA P02545 1/20 0.47
FKBP1A P62942 4/20 0.46
ALDH1A1 P00352 2/20 0.46
HTT P42858 1/20 0.46
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
GAA P10253 1/20 0.45
ALOX15 P16050 1/20 0.44
HSD17B10 Q99714 1/20 0.44
RAB9A P51151 1/20 0.44
GLA P06280 1/20 0.44
HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8483449 0.84 L3MBTL1 (0.48) L3MBTL1POLBALDH1A1MEN1KMT2A
SCHEMBL8488421 0.82 L3MBTL1 (0.50) L3MBTL1POLBALDH1A1HTTMEN1
SCHEMBL8488474 0.81 L3MBTL1 (0.48) L3MBTL1TSHRPOLBLMNAFKBP1A
SCHEMBL8484571 0.81 L3MBTL1 (0.52) L3MBTL1TSHRPOLBLMNAFKBP1A
SCHEMBL27409350 0.79 MEN1 (0.47) L3MBTL1TSHRPOLBLMNAFKBP1A
SCHEMBL294992 0.79 POLB (0.55) L3MBTL1TSHRPOLBLMNAFKBP1A
SCHEMBL19574096 0.78 SMN1; SMN2 (0.49) L3MBTL1TSHRPOLBLMNAFKBP1A
SCHEMBL8484573 0.77 L3MBTL1 (0.52) L3MBTL1TSHRPOLBLMNAFKBP1A
SCHEMBL3818013 0.76 L3MBTL1 (0.55) L3MBTL1TSHRPOLBLMNAFKBP1A
SCHEMBL1456109 0.76 L3MBTL1 (0.59) L3MBTL1TSHRPOLBLMNAFKBP1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5958837-A 2-(PHENYLMETHOXY OR CARBONYLOXY-(1,4-PHENYLENE)-),3-HALO,5-HALOALKYLPYRIDINES; HERBICIDES EFFECTING DESICCATION AND DEFOLIATION OF PLANTS; GOOD ACTIVITY AND BETTER TAILORED CONTROL OF WEEDS BASF AKTIENGESELLSCHAFT (DE) 1999-09-28 US disclosed
EP-0802904-B1 SUBSTITUTED 2-PHENYLPYRIDINES AS HERBICIDES BASF AG (DE) 1998-09-09 EP disclosed
CN-1172477-A Substituted 2 -phenylpyridines as herbicides BASF AG (DE) 1998-02-04 CN disclosed