SCHEMBL848854

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28466660	0.86	MEN1 (0.78)	MEN1KMT2AKDM4EALDH1A1TPSAB1
	SCHEMBL5465071	0.86	MEN1 (1.00)	MEN1KMT2AKDM4EPDGFRBPDGFRA
	SCHEMBL3126965	0.86	NPC1 (0.57)	MEN1KMT2AKDM4EPDGFRBPDGFRA
	SCHEMBL5474021	0.85	MEN1 (0.76)	MEN1KMT2AKDM4EALDH1A1TPSAB1
	SCHEMBL5466273	0.85	KMT2A (0.76)	MEN1KMT2AKDM4EPDGFRBPDGFRA
	SCHEMBL5471150	0.84	MEN1 (0.75)	MEN1KMT2AKDM4EALDH1A1TPSAB1
	SCHEMBL5466489	0.82	MEN1 (0.72)	MEN1KMT2APDGFRBPDGFRAMAPT
	SCHEMBL5466245	0.82	MEN1 (0.72)	MEN1KMT2AKDM4EALDH1A1TPSAB1
	SCHEMBL29682382	0.82	MEN1 (0.51)	MEN1KMT2AKDM4EPDGFRBPDGFRA
	SCHEMBL13621149	0.82	MEN1 (0.71)	MEN1KMT2AKDM4EALDH1A1HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.