Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 7/20 | 0.51 |
| ▸ | TYK2 | P29597 | 7/20 | 0.51 |
| ▸ | JAK1 | P23458 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8475365 | 0.82 | JAK2 (0.47) | JAK2TYK2JAK1MEN1KMT2A | |
| SCHEMBL8486949 | 0.82 | MEN1 (0.54) | JAK2TYK2JAK1MEN1KMT2A | |
| SCHEMBL6537461 | 0.82 | TYK2 (0.57) | JAK2TYK2JAK1MEN1KMT2A | |
| SCHEMBL6537668 | 0.80 | TYK2 (0.55) | JAK2TYK2JAK1MEN1KMT2A | |
| SCHEMBL6538203 | 0.80 | TYK2 (0.55) | JAK2TYK2JAK1MEN1KMT2A | |
| SCHEMBL6538073 | 0.80 | TYK2 (0.56) | JAK2TYK2JAK1MEN1KMT2A | |
| SCHEMBL8489319 | 0.79 | TYK2 (0.54) | JAK2TYK2JAK1MEN1KMT2A | |
| SCHEMBL6537767 | 0.78 | TYK2 (0.53) | JAK2TYK2JAK1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6538361 | 0.78 | JAK2 (0.49) | JAK2TYK2JAK1MEN1KMT2A | |
| SCHEMBL6537375 | 0.78 | CCNC (0.48) | JAK2TYK2JAK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999021835-A1 | QUINOLINE DERIVATIVES AS H+-ATPase INHIBITORS AND AS BONE RESORPTION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-05-06 | — | — | WO | disclosed |