Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.54 |
| ▸ | DRD3 | P35462 | 4/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | DRD5 | P21918 | 1/20 | 0.54 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 4/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28221729 | 0.89 | S1PR3 (0.52) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL18616368 | 0.86 | HTR2C (0.40) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL20671935 | 0.81 | DRD2 (0.37) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL4379176 | 0.81 | DRD3 (0.67) | DRD2DRD3DRD1DRD4DRD5 | |
| Hydrochloric Acid SCHEMBL7994687 | 0.79 | DRD3 (0.65) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL18585843 | 0.79 | CHRNB4 (0.49) | DRD2DRD3HTR2CSLC6A2SLC6A3 | |
| SCHEMBL17825519 | 0.78 | SPHK1 (0.44) | — | |
| SCHEMBL11830694 | 0.77 | DRD2 (0.55) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL11828822 | 0.74 | HTR2C (0.55) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL20671885 | 0.74 | DRD2 (0.43) | DRD2DRD3DRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997474-B1 | Antithrombotic agents | PFIZER (US) | 2003-10-29 | — | — | EP | disclosed |