Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GRN | P28799 | 1/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489260 | 0.86 | HDAC7 (0.47) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL3749007 | 0.78 | SMN1; SMN2 (0.46) | MMP2MMP9SMN1; SMN2HDAC7POLB | |
| SCHEMBL8490162 | 0.78 | ALDH1A1 (0.51) | SMN1; SMN2POLB | |
| SCHEMBL8486107 | 0.78 | HDAC1 (0.45) | MMP2MMP9SMN1; SMN2HDAC7HDAC1 | |
| SCHEMBL2438598 | 0.77 | SMN1; SMN2 (0.45) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL8490395 | 0.77 | FNTA (0.47) | MMP2MMP9SMN1; SMN2HDAC7PKM | |
| SCHEMBL8489619 | 0.76 | CA12 (0.47) | MMP2MMP9SMN1; SMN2HDAC7POLB | |
| SCHEMBL3183424 | 0.76 | SMN1; SMN2 (0.41) | SMN1; SMN2PKM | |
| SCHEMBL31649054 | 0.76 | AKT1 (0.49) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL28538006 | 0.76 | AKT1 (0.49) | MMP2MMP3MMP9MMP13MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999041242-A1 | DI-SUBSTITUTED NAPHTHYL DERIVATIVES, PREPARATION THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1999-08-19 | — | — | WO | disclosed |