Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | BCR | P11274 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488384 | 0.86 | MAPT (0.38) | ALDH1A1MAPT | |
| SCHEMBL8492700 | 0.86 | MAPK1 (0.36) | SMN1; SMN2ALDH1A1MAPTRAB9AMAPK1 | |
| SCHEMBL8489087 | 0.86 | HTT (0.41) | SMN1; SMN2ALDH1A1POLBCYP2C19CYP1A2 | |
| SCHEMBL8492588 | 0.84 | HPD (0.51) | ALDH1A1POLBCYP2C19CYP1A2CYP3A4 | |
| SCHEMBL8492606 | 0.83 | HPD (0.40) | ALDH1A1CYP2C19CYP1A2CYP3A4HPGD | |
| SCHEMBL8493348 | 0.83 | MEN1 (0.41) | ALDH1A1POLBHTTMEN1KMT2A | |
| SCHEMBL8492872 | 0.83 | DHODH (0.33) | ALDH1A1HPGDHTTMEN1KMT2A | |
| SCHEMBL8494532 | 0.83 | DHODH (0.49) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL8045057 | 0.83 | DHODH (0.35) | SMN1; SMN2ALDH1A1POLBHTTMAPT | |
| SCHEMBL8495049 | 0.83 | POLB (0.51) | SMN1; SMN2ALDH1A1POLBCYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859283-A | TERTIARY-BUTYL 3-CYCLOALKYL-3-OXOPROPIONATE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| US-5747424-A | HEATING AN AROMATIC DIKETONE WITH A SALT OF HYDROXYLAMINE IN A SOLVENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-05-05 | — | — | US | disclosed |
| US-5656573-A | Herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-12 | — | — | US | disclosed |
| US-5650533-A | Intermediates to herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-22 | — | — | US | disclosed |
| WO-1995022904-A1 | PESTICIDAL METHOD | RHONE POULENC AGROCHIMIE (FR) | 1995-08-31 | — | — | WO | disclosed |