Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 20/20 | 0.79 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8485022 | 0.94 | GRIN1 (0.78) | GRIN1 | |
| SCHEMBL8930661 | 0.92 | GRIN1 (0.74) | GRIN1 | |
| SCHEMBL7586603 | 0.90 | GRIN1 (0.79) | GRIN1 | |
| SCHEMBL8486525 | 0.88 | GRIN1 (1.00) | GRIN1 | |
| SCHEMBL7465495 | 0.78 | GRIN1 (1.00) | GRIN1 | |
| SCHEMBL8484920 | 0.77 | GRIN1 (0.59) | GRIN1 | |
| SCHEMBL8485635 | 0.76 | GRIN1 (0.78) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| Uk-240455 SCHEMBL6906418 | 0.76 | GRIN1 (0.86) | GRIN1 | |
| SCHEMBL8485623 | 0.76 | GRIN1 (0.79) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8484806 | 0.76 | GRIN1 (0.64) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5863917-A | ANXIOLYTIC AGENT, ANTICONVULSANTS, ANALGESICS AND NEUROPROTECTIVES. | PFIZER, INC. (US) | 1999-01-26 | — | — | US | disclosed |
| EP-0792874-A1 | Quinoxaline derivatives useful in therapy | Pfizer Limited (GB) | 1997-09-03 | — | — | EP | disclosed |