Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPD | P32754 | 1/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 8/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8491867 | 0.85 | HPD (0.49) | HPDMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL8491768 | 0.84 | HPD (0.48) | HPDMAPTKMT2ARAB9AALDH1A1 | |
| SCHEMBL15103042 | 0.83 | HPD (0.47) | HPDMAPTKMT2AMEN1ABCB1 | |
| SCHEMBL8488945 | 0.83 | HPD (0.56) | HPDMAPTKMT2ARAB9AMEN1 | |
| SCHEMBL8491955 | 0.83 | HPD (0.47) | HPDMAPTRAB9AALDH1A1 | |
| SCHEMBL8492060 | 0.83 | HPD (0.50) | HPDMAPTKMT2AALDH1A1 | |
| SCHEMBL8494434 | 0.81 | HPD (0.46) | HPDVCAM1MAPTKMT2ARAB9A | |
| SCHEMBL8489402 | 0.81 | HPD (0.69) | HPDMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL8492861 | 0.79 | HPD (0.57) | HPDMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL8489202 | 0.74 | GSK3B (0.52) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859283-A | TERTIARY-BUTYL 3-CYCLOALKYL-3-OXOPROPIONATE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| US-5747424-A | HEATING AN AROMATIC DIKETONE WITH A SALT OF HYDROXYLAMINE IN A SOLVENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-05-05 | — | — | US | disclosed |
| US-5656573-A | Herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-12 | — | — | US | disclosed |
| US-5650533-A | Intermediates to herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-22 | — | — | US | disclosed |
| EP-0418175-B1 | Isoxazoles herbicides | RHONE POULENC AGRICULTURE (GB) | 1996-07-17 | — | — | EP | disclosed |
| EP-0418175-A2 | Isoxazoles herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1991-03-20 | — | — | EP | disclosed |