Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488066 | 0.86 | GCK (0.39) | KDM4ETDP1PARP1 | |
| SCHEMBL8486440 | 0.85 | KDM4E (0.36) | KDM4ETDP1PARP1 | |
| SCHEMBL8489555 | 0.83 | NPC1 (0.45) | KDM4E | |
| SCHEMBL8489999 | 0.83 | ABL1 (0.38) | — | |
| SCHEMBL8489156 | 0.83 | KDM4E (0.39) | KDM4EGAA | |
| SCHEMBL8488589 | 0.81 | MEN1 (0.44) | KDM4ETDP1 | |
| SCHEMBL8487080 | 0.81 | EPHX1 (0.45) | — | |
| SCHEMBL8488059 | 0.80 | POLB (0.56) | KDM4E | |
| SCHEMBL8486963 | 0.78 | MAPK1 (0.41) | KDM4E | |
| SCHEMBL8486913 | 0.78 | POLB (0.41) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999021835-A1 | QUINOLINE DERIVATIVES AS H+-ATPase INHIBITORS AND AS BONE RESORPTION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-05-06 | — | — | WO | disclosed |