Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489380 | 1.00 | KDM4E (0.46) | KDM4EPARP1CA1CA2NFKB1 | |
| SCHEMBL6683114 | 0.94 | PARP1 (0.48) | KDM4EPARP1CA1CA2NFKB1 | |
| SCHEMBL6683109 | 0.94 | PARP1 (0.48) | KDM4EPARP1CA1CA2NFKB1 | |
| SCHEMBL3800012 | 0.84 | PTPN1 (0.47) | NFKB1PTPN1MAOAMAOB | |
| SCHEMBL29952108 | 0.84 | PTPN1 (0.47) | NFKB1PTPN1MAOAMAOB | |
| SCHEMBL8488520 | 0.76 | KDM4E (0.43) | KDM4EPARP1CA1CA2NFKB1 | |
| SCHEMBL8488522 | 0.76 | KDM4E (0.43) | KDM4EPARP1CA1CA2NFKB1 | |
| SCHEMBL22409645 | 0.74 | CDK4 (0.43) | KDM4ENFKB1CYP3A4MAPTPTPN1 | |
| SCHEMBL22409644 | 0.74 | CDK4 (0.43) | KDM4ENFKB1CYP3A4MAPTPTPN1 | |
| SCHEMBL6682378 | 0.74 | TRPM8 (0.38) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856529-A | ADJUSTMENT OF NERVOUS SYSTEM, ENDOCRINE FUNCTION; REPRODUCTION, BODY WEIGHT AND METABOLISM | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-01-05 | — | — | US | disclosed |