Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.50 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.50 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | NQO1 | P15559 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8486987 | 0.98 | MAOA (0.54) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL8495123 | 0.98 | MAOA (0.54) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6273118 | 0.93 | ALDH2 (0.51) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6276289 | 0.93 | ALDH2 (0.51) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6277750 | 0.93 | ALDH2 (0.51) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6276950 | 0.93 | ALDH2 (0.53) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6271588 | 0.93 | ALDH2 (0.51) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6275616 | 0.93 | ALDH2 (0.53) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6276949 | 0.93 | ALDH2 (0.53) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL6270736 | 0.93 | ALDH2 (0.51) | KDM4EALDH1A1HPGDTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1101678-C | Benzopyran derivative and therapeutic agent for heart disease containing the same as active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2003-02-19 | — | — | CN | disclosed |
| US-5981495-A | TREATING HEART DISEASE BY ADMINISTERING TO THE HEART PATIENT A BENOPYRAN DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-11-09 | — | — | US | disclosed |
| CN-1164999-A | Benzopyran derivative and therapeutic agent for heart disease containing the same as active ingredient | DAINIPPON INK & CHEMICALS (JP) | 1997-11-19 | — | — | CN | disclosed |
| EP-0796854-A1 | Benzopyran derivative and use of said benzopyran derivative for treating heart disease | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-09-24 | — | — | EP | disclosed |