Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.66 |
| ▸ | NPC1 | O15118 | 5/20 | 0.66 |
| ▸ | HTT | P42858 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | GALR3 | O60755 | 2/20 | 0.64 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TNF | P01375 | 2/20 | 0.52 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8506416 | 0.87 | SMN1; SMN2 (0.66) | RAB9ANPC1HTTSMN1; SMN2LMNA | |
| SCHEMBL5423236 | 0.83 | RAB9A (0.73) | RAB9ANPC1HTTSMN1; SMN2LMNA | |
| SCHEMBL9607967 | 0.82 | NPC1 (0.60) | RAB9ANPC1HTTSMN1; SMN2LMNA | |
| SCHEMBL3966396 | 0.82 | HTT (0.68) | RAB9ANPC1HTTSMN1; SMN2LMNA | |
| SCHEMBL8515676 | 0.80 | MEN1 (0.56) | RAB9ANPC1HTTSMN1; SMN2LMNA | |
| SCHEMBL8505626 | 0.79 | HTT (0.68) | RAB9ANPC1HTTSMN1; SMN2LMNA | |
| SCHEMBL8515771 | 0.79 | HTT (0.64) | RAB9ANPC1HTTSMN1; SMN2LMNA | |
| SCHEMBL13242726 | 0.78 | HTT (0.58) | RAB9ANPC1HTTSMN1; SMN2LMNA | |
| SCHEMBL8490156 | 0.78 | HTT (0.60) | RAB9ANPC1HTTSMN1; SMN2LMNA | |
| SCHEMBL17456981 | 0.78 | SMN1; SMN2 (1.00) | RAB9ANPC1HTTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2455371-A1 | 4-(3-BUTYNYL)AMINOPYRIMIDINE DERIVATIVES AS PEST CONTROL AGENTS FOR AGRICULTURAL AND HORTICULTURAL USE | SDS Biotech K. K. (JP) | 2012-05-23 | — | — | EP | disclosed |