Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.78 |
| ▸ | MEN1 | O00255 | 5/20 | 0.78 |
| ▸ | TNF | P01375 | 2/20 | 0.78 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.78 |
| ▸ | HTT | P42858 | 4/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | GALR3 | O60755 | 1/20 | 0.67 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8490055 | 0.86 | KMT2A (0.61) | KMT2AMEN1TNFNOD1HTT | |
| SCHEMBL8482830 | 0.85 | MEN1 (0.57) | KMT2AMEN1TNFNOD1HTT | |
| SCHEMBL8504006 | 0.84 | HTT (0.64) | KMT2AMEN1TNFNOD1HTT | |
| SCHEMBL8490348 | 0.83 | HTT (0.65) | KMT2AMEN1TNFNOD1HTT | |
| SCHEMBL8515676 | 0.82 | MEN1 (0.56) | KMT2AMEN1TNFNOD1HTT | |
| SCHEMBL8505625 | 0.81 | HTT (0.64) | KMT2AMEN1TNFNOD1HTT | |
| SCHEMBL8482940 | 0.81 | MEN1 (0.77) | KMT2AMEN1TNFNOD1HTT | |
| SCHEMBL8483285 | 0.80 | APP (0.68) | KMT2AMEN1HTTSMN1; SMN2LMNA | |
| SCHEMBL17456981 | 0.80 | SMN1; SMN2 (1.00) | KMT2AMEN1TNFNOD1HTT | |
| SCHEMBL3341524 | 0.79 | RAB9A (0.64) | KMT2AMEN1TNFNOD1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2455371-A1 | 4-(3-BUTYNYL)AMINOPYRIMIDINE DERIVATIVES AS PEST CONTROL AGENTS FOR AGRICULTURAL AND HORTICULTURAL USE | SDS Biotech K. K. (JP) | 2012-05-23 | — | — | EP | disclosed |