Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8490244 | 0.92 | POLB (0.46) | KDM4EALDH1A1HPGDMEN1GAA | |
| SCHEMBL8489184 | 0.90 | ALDH1A1 (0.45) | KDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL8489929 | 0.90 | MAPT (0.51) | KDM4EALDH1A1HSD17B10LCKMAPK14 | |
| SCHEMBL8492043 | 0.83 | POLB (0.44) | KDM4EALDH1A1TDP1L3MBTL1LMNA | |
| SCHEMBL8487107 | 0.81 | TYK2 (0.42) | LCKMAPK14MEN1KMT2ALMNA | |
| SCHEMBL8490225 | 0.81 | TYK2 (0.41) | LCKMAPK14TDP1MEN1KMT2A | |
| SCHEMBL6537770 | 0.80 | TYK2 (0.43) | ALDH1A1MEN1KMT2ALMNAPOLB | |
| SCHEMBL8486665 | 0.80 | TYK2 (0.41) | LCKMAPK14MEN1KMT2ALMNA | |
| SCHEMBL8486950 | 0.80 | KMT2A (0.48) | KDM4EALDH1A1TRPV1MEN1KMT2A | |
| SCHEMBL8490099 | 0.79 | MEN1 (0.46) | KDM4EHSD17B10MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999021835-A1 | QUINOLINE DERIVATIVES AS H+-ATPase INHIBITORS AND AS BONE RESORPTION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-05-06 | — | — | WO | disclosed |