SCHEMBL8490618

SCHEMBL8490618

O=C(Oc1c(O)c2ccc(O)cc2oc1=O)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAP1LC3B Q9GZQ8 3/20 0.53
MAP1LC3A Q9H492 3/20 0.53
NQO1 P15559 3/20 0.52
NPSR1 Q6W5P4 2/20 0.51
RXFP1 Q9HBX9 1/20 0.51
ALDH1A1 P00352 5/20 0.47
HPGD P15428 2/20 0.47
MIF P14174 2/20 0.47
ERAP1 Q9NZ08 1/20 0.47
KMT2A Q03164 5/20 0.47
MAPT P10636 4/20 0.47
GAA P10253 4/20 0.47
KDM4E B2RXH2 4/20 0.47
MEN1 O00255 3/20 0.47
GLA P06280 2/20 0.47
LMNA P02545 2/20 0.47
MGAM O43451 1/20 0.47
NR1I2 O75469 1/20 0.47
ESR1 P03372 1/20 0.47
POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8491606 0.91 NPSR1 (0.52) MAP1LC3BMAP1LC3ANQO1NPSR1RXFP1
SCHEMBL8490540 0.90 NQO1 (0.52) MAP1LC3BMAP1LC3ANQO1NPSR1RXFP1
SCHEMBL8495376 0.90 KMT2A (0.49) MAP1LC3BMAP1LC3ANPSR1RXFP1ALDH1A1
SCHEMBL12903267 0.86 ALDH1A1 (0.60) NQO1NPSR1ALDH1A1KMT2AMAPT
SCHEMBL8496994 0.86 GAA (0.49) MAP1LC3BMAP1LC3ANPSR1RXFP1ALDH1A1
SCHEMBL8497342 0.86 GAA (0.49) MAP1LC3BMAP1LC3ANPSR1RXFP1ALDH1A1
SCHEMBL8494027 0.85 NPSR1 (0.47) MAP1LC3BMAP1LC3ANQO1NPSR1RXFP1
SCHEMBL8492630 0.85 NPSR1 (0.47) MAP1LC3BMAP1LC3ANQO1NPSR1RXFP1
SCHEMBL8493928 0.85 NQO1 (0.55) NQO1ALDH1A1HPGDKMT2AMAPT
SCHEMBL8493473 0.84 KDM4E (0.56) NPSR1RXFP1ALDH1A1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0598117-B1 BENZOPYRAN DERIVATIVE AND ANTIALLERGIC AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT DAINIPPON INK & CHEMICALS (JP) 1999-06-30 EP disclosed
US-5428059-A Benzopyran derivatives and an anti-allergic agent possessing the same as the active ingredient DAINIPPON INK & CHEMICALS, INC. (JP) 1995-06-27 US disclosed
EP-0598117-A1 BENZOPYRAN DERIVATIVE AND ANTIALLERGIC AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT DAINIPPON INK AND CHEMICALS, INC. (JP) 1994-05-25 EP disclosed