Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.40 |
| ▸ | PAM | P19021 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL538524 | 0.80 | CYP19A1 (0.76) | KMT2AHPGDCYP19A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL30349563 | 0.80 | CYP4F2 (0.45) | KMT2AMEN1GPR84ALDH1A1 | |
| SCHEMBL6179185 | 0.79 | AKR1B1 (0.54) | KMT2AL3MBTL1MEN1GPR84CES2 | |
| SCHEMBL11131614 | 0.78 | CYP19A1 (0.73) | KMT2AHPGDCYP19A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL28795788 | 0.78 | CYP19A1 (0.73) | KMT2AHPGDCYP19A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL28071098 | 0.78 | CYP19A1 (0.73) | KMT2AHPGDCYP19A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL8365863 | 0.78 | CYP19A1 (0.73) | KMT2AHPGDCYP19A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL4205339 | 0.78 | CYP19A1 (0.73) | KMT2AHPGDCYP19A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL11759023 | 0.78 | CYP19A1 (0.73) | KMT2AHPGDCYP19A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL27858507 | 0.78 | CYP19A1 (0.73) | KMT2AHPGDCYP19A1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999001442-A1 | TRIAZINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | ZENECA LIMITED (GB) | 1999-01-14 | — | — | WO | disclosed |