Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 10/20 | 1.00 |
| ▸ | GRM7 | Q14831 | 10/20 | 1.00 |
| ▸ | GRM2 | Q14416 | 9/20 | 1.00 |
| ▸ | GRM4 | Q14833 | 9/20 | 1.00 |
| ▸ | GRM3 | Q14832 | 6/20 | 1.00 |
| ▸ | GRM1 | Q13255 | 6/20 | 1.00 |
| ▸ | GRM5 | P41594 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15060588 | 1.00 | GRM8 (1.00) | GRM8GRM7GRM2GRM4GRM3 | |
| SCHEMBL29389814 | 1.00 | GRM8 (1.00) | GRM8GRM7GRM2GRM4GRM3 | |
| SCHEMBL30079684 | 1.00 | GRM8 (1.00) | GRM8GRM7GRM2GRM4GRM3 | |
| SCHEMBL481153 | 1.00 | GRM8 (1.00) | GRM8GRM7GRM2GRM4GRM3 | |
| SCHEMBL13746359 | 1.00 | GRM8 (1.00) | GRM8GRM7GRM2GRM4GRM3 | |
| SCHEMBL24606222 | 1.00 | GRM8 (1.00) | GRM8GRM7GRM2GRM4GRM3 | |
| SCHEMBL5202158 | 1.00 | GRM8 (1.00) | GRM8GRM7GRM2GRM4GRM3 | |
| SCHEMBL12019053 | 1.00 | GRM8 (1.00) | GRM8GRM7GRM2GRM4GRM3 | |
| SCHEMBL7393500 | 0.84 | GRM8 (0.72) | GRM8GRM7GRM2GRM4GRM3 | |
| SCHEMBL7386669 | 0.84 | GRM8 (0.72) | GRM8GRM7GRM2GRM4GRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771196-B1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 1999-12-08 | — | — | EP | disclosed |
| US-5717109-A | CARBOXYCYCLOPROPYL GLYCINE DERIVATIVES; USEFUL FOR TREATMENT OF ACUTE OR CHRONIC NEURODEGENERATIVE CONDITIONS, AND AS ANTIPSYCHOTIC, ANTICONVULSANT, ANALGESIC, ANXIOLYTIC, ANTIDEPRESSANT AND ANTI-EMETIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-02-10 | — | — | US | disclosed |